Anticholinergic substances: A single consistent conformation.

Endogenous anticholinergic substances may exist during acute illness in elderly medical patients.

BACKGROUND The purpose of this study was to determine if serum anticholinergic activity (SACA) arises from endogenous substances produced during illness. METHODS Elderly medical inpatients (N = 612) were screened for anticholinergic medication use in the week prior to the study by interviews of subjects and proxies and review of emergency room, hospital, and nursing home medication administra...

Carrier Determination in a Hemophilia B Family Using Single Strand Conformation Polymorphism (SSCP) and Sequencing

BRONCHODILATORY AND ANTICHOLINERGIC EFFECTS OF CARUM CARVI ON ISOLATED GUINEA PIG TRACHEAL CHAINS

Carum carvi (CC) is a grassy plant which is believed to have several therapeutic effects, including anti-asthmatic properties. We have therefore studied the bronchodilatory and anticholinergic effects of this plant. The bronchodilatory effects of the aqueous extract (AE), macerated extract (ME), essential oil (EO), and 4µM theophylline (T) in comparison with saline (S) were examined by the...

Bronchodilatory and anticholinergic effects of Polygonum avicular on isolated tracheal chains of the guinea pig

  In this study we investigated the bronchodilatory and anticholinergic effects of the aqueous extract (AE), brewed extract (BE) and ethanol extract (EE) of Polygonum avicular in comparison with saline (S) on isolated tracheal chains of the guinea pig. Due to the probable confounding effect of ethanol in the EE, the effects of this extract were also compared with 96 % ethanol. None of the plant...

Belladonna Alkaloid Intoxication: The 10-Year Experience of a Large Tertiary Care Pediatric Hospital.

The belladonna alkaloids can be isolated from a number of plants, which contain hallucinogens that represent a serious danger to infants, children, and adolescents. Roots, leaves, and fruits of the plant contain the alkaloids atropine, hyoscyamine, and scopolamine, which can lead to an anticholinergic toxidrome; however, not all characteristics of the toxidrome are necessarily present in each c...